December 1, 2022

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NodThera Appoints Chief Clinical Officer and Chief Economical Officer

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CAMBRIDGE, England & BOSTON & SEATTLE–(Company WIRE)–Dec 15, 2020–

NodThera, a biotechnology organization developing a new class of medicines that inhibit the NLRP3 inflammasome to treat continual inflammation, today declared the expansion of its senior management team with the appointments of Donald Johns, M.D., as Main Healthcare Officer and Katina Dorton, J.D., MBA, as Main Economic Officer.

Dr. Johns is an accomplished drug progress leader and board-accredited scientific neurologist who formerly served as Chief Health care Officer and Government Vice President of Medical and Scientific Affairs at Syntimmune, prior to the company’s acquisition by Alexion Pharmaceuticals. Ms. Dorton is a acknowledged and internationally expert fiscal executive, company director and public organization CFO. Ms. Dorton’s field skills consists of roles in healthcare, existence sciences and financial investment banking, like activities at Repare Therapeutics and AVROBIO, Inc.

NodThera is advancing a portfolio of powerful and selective inhibitors of the NLRP3 inflammasome that minimize each IL-1β and IL-18, professional-inflammatory cytokines which are recognised to perform a part in chronic irritation underlying a vast range of disorders. The pipeline involves brain penetrant NLRP3 inhibitors for central nervous process (CNS) indications.

“We welcome Don and Katina to the workforce as we continue on to advance our portfolio of differentiated NLRP3 inhibitors to capitalize on the prospect to exploit the very well-comprehended, but still untapped therapeutic likely of the NLRP3 inflammasome across a wide spectrum of conditions,” mentioned Adam Keeney, Ph.D., President & Main Executive Officer of NodThera. “Don is an accomplished clinician with an impressive monitor document who brings a wealth of modern scientific improvement practical experience. Katina brings capital marketplaces working experience and has constructed economic, authorized and operational features to support firms by intense expansion, which includes IPO preparing. Their combined contributions will increase considerable worth as we keep on to advance NodThera’s portfolio through medical growth and more financing rounds.”

“The NLRP3 inflammasome is a person of the most thrilling rising areas of therapeutic science. NodThera’s most effective-in-class molecules have wonderful prospective to deal with the unmet professional medical have to have in patients with a extensive array of inflammatory diseases,” stated Dr. Johns. Ms. Dorton provides, “By leveraging innate immunity, NodThera’s system has the prospective to blaze a new route forward in a broad array of conditions, and I am thrilled to be part of the rest of the experienced management staff in this effort.”

Dr. Johns delivers a lot more than 25 decades of working experience in the progress of novel therapies for severe diseases, including autoimmune and CNS ailments. Prior to his purpose at Syntimmune, Dr. Johns served in important leadership positions at Biogen and the Novartis Institutes for Biomedical Study (NIBR). He has contributed to various investigational new drug purposes (INDs), first-in-human reports and conclusive evidence-of-concept reports in a wide spectrum of CNS and autoimmune health conditions, as properly as 4 effective new drug purposes (NDAs). Prior to joining the pharmaceutical field, he was a neurologist clinician-scientist at Johns Hopkins and Harvard Medical School. Dr. Johns attained his B.A. from Vanderbilt College and his M.D. from the Yale University School of Medication.

Ms. Dorton now serves on the board of directors for Fulcrum Therapeutics (Nasdaq: FULC), Pandion Therapeutics, Inc. (Nasdaq: PAND) and US Ecology (Nasdaq: ECOL). She most just lately served as Chief Monetary Officer of Repare Therapeutics, a artificial lethality and DNA fix-concentrated oncology business. Prior to Repare, Ms. Dorton served as Main Money Officer of AVROBIO, a lentiviral gene remedy business. Previously in her occupation, she served as a taking care of director in financial investment banking for Morgan Stanley and Needham & Company and as an associate legal professional at Sullivan & Cromwell. Ms. Dorton been given her J.D. from the University of Virginia University of Legislation, her MBA from George Washington College and her B.A. from Duke College.

About NodThera

NodThera is a biotechnology business establishing a new class of potent and selective NLRP3 inflammasome inhibitors for the remedy of ailments pushed by chronic irritation. Led by an experienced administration team, NodThera is leveraging new insights into inflammasome biology and chemistry to create a system of really differentiated small molecule NLRP3 inhibitors. The enterprise was established by Epidarex Capital and even more financed by 5AM Ventures, Cowen Health care Investments, F-Primary Capital, Novo Holdings, Sanofi Ventures and Sofinnova Associates. NodThera was launched in 2016 and maintains places of work in Cambridge, United kingdom, Seattle, WA and Boston, MA. For a lot more info be sure to take a look at www.nodthera.com.

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PUB: 12/15/2020 08:00 AM/DISC: 12/15/2020 08:01 AM

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